{"id":7382,"date":"2024-04-01T07:34:18","date_gmt":"2024-03-31T22:34:18","guid":{"rendered":"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/?p=7382"},"modified":"2024-04-01T13:02:04","modified_gmt":"2024-04-01T04:02:04","slug":"puberulic-acid","status":"publish","type":"post","link":"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/puberulic-acid\/","title":{"rendered":"\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u306f\uff1f\u30d7\u30d9\u30eb\u30eb\u9178\u306e\u6bd2\u6027\u3068\u7d05\u9eb9\u3068\u306e\u95a2\u4fc2\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u5c0f\u6797\u88fd\u85ac\u306e\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u691c\u51fa\u3055\u308c\u305f\u3068\u3055\u308c\u308b\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u300d\u3002\u307f\u306a\u3055\u3093\u3082\u805e\u3044\u305f\u3053\u3068\u304c\u306a\u3044\u6210\u5206\u3067\u30d3\u30c3\u30af\u30ea\u3057\u305f\u3053\u3068\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u306b\u3064\u3044\u3066<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u306f\u4f55\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30d9\u30eb\u30eb\u9178\u306e\u6bd2\u6027\u306f\u3069\u308c\u304f\u3089\u3044\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb4\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u95a2\u4fc2\u306f\u3042\u308b\u306e\u304b<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u542b\u3081\u3066\u3001\u69d8\u3005\u306a\u8ad6\u6587\u304b\u3089\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u7d05\u9eb9\u3084\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3064\u3044\u3066\u306f<strong><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/red-yeast-rice\/\" title=\"\">\u7d05\u9eb9\u3068\u306f\uff1f\u7d05\u9eb9\u306e\u52b9\u679c\u3068\u5371\u967a\u6027\u306b\u3064\u3044\u3066\u3010\u81ea\u4e3b\u56de\u53ce\u3011<\/a><\/strong>\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/mark><\/p>\n\n\n<ins class=\"adsbygoogle\"\n        style=\"display:block; text-align:center;\"\n        data-ad-layout=\"in-article\"\n        data-ad-format=\"fluid\"\n        data-ad-client=\"ca-pub-5748007460615735\"\n        data-ad-slot=\"4711491386\"><\/ins>\n        <script>\n        (adsbygoogle = window.adsbygoogle || []).push({});\n        <\/script>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #4bd151;color:#4bd151\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #4bd151;color:#4bd151\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/puberulic-acid\/#%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%A8%E3%81%AF%EF%BC%9F\" >\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/puberulic-acid\/#%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%AE%E6%AF%92%E6%80%A7%E3%81%AF%EF%BC%9F\" >\u30d7\u30d9\u30eb\u30eb\u9178\u306e\u6bd2\u6027\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/puberulic-acid\/#%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%A8%E7%B4%85%E9%BA%B9%E3%82%B5%E3%83%97%E3%83%AA%E3%83%A1%E3%83%B3%E3%83%88%E3%81%A8%E3%81%AE%E9%96%A2%E4%BF%82%E3%81%AF%EF%BC%9F\" >\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u306e\u95a2\u4fc2\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/puberulic-acid\/#%E3%81%82%E3%82%8F%E3%81%9B%E3%81%A6%E3%81%93%E3%81%A1%E3%82%89%E3%82%82%E3%82%AA%E3%82%B9%E3%82%B9%E3%83%A1%E3%81%A7%E3%81%99\" >\u3042\u308f\u305b\u3066\u3053\u3061\u3089\u3082\u30aa\u30b9\u30b9\u30e1\u3067\u3059<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%A8%E3%81%AF%EF%BC%9F\"><\/span>\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T071706.737.webp\" alt=\"\" class=\"wp-image-7385 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T071706.737.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T071706.737-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T071706.737-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d7\u30d9\u30eb\u30eb\u9178\u306f\u9752\u30ab\u30d3\u306e\u4e00\u7a2e\u306e\u4ee3\u8b1d\u7523\u7269\u304b\u3089\u898b\u3064\u304b\u3063\u305f\u5929\u7136\u5316\u5408\u7269\u3067\u3059\u3002\u9ec4\u8272\u3044\u7c89\u672b\u72b6\u306e\u5316\u5408\u7269\u3067\u5316\u5b66\u5f0f\u306f\u300cC8H6O6\u300d\u3002\u30de\u30e9\u30ea\u30a2\u6cbb\u7642\u306e\u305f\u3081\u306e\u6709\u671b\u306a\u5929\u7136\u7269\u8cea\u3068\u3057\u3066\u3001\u30da\u30cb\u30b7\u30ea\u30a6\u30e0\u30fb\u30f4\u30a3\u30c6\u30a3\u30b3\u30e9\uff08FKI-4410\uff09\u306e\u57f9\u990a\u6db2\u304b\u3089\u5206\u96e2\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5206\u96e2\u5b9f\u9a13\u306e\u8ad6\u6587\u3067\u306f\u3001\u5c71\u68a8\u770c\u7523\u306e\u30d6\u30c9\u30a6\u3092\u767a\u9175\u3055\u305b\u3066\u3067\u304d\u305f\u30ab\u30d3\u3092\u7528\u3044\u3066\u3044\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30e9\u30ea\u30a2\u306e\u6cbb\u7642\u85ac\u3068\u3044\u3048\u3070\u300c\u30af\u30ed\u30ed\u30ad\u30f3\u300d\u304c\u6709\u540d\u3067\u3059\u304c\u3001\u30af\u30ed\u30ed\u30ad\u30f3\u8010\u6027\u30de\u30e9\u30ea\u30a2\u304c\u554f\u984c\u8996\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u3001\u30da\u30cb\u30b7\u30ea\u30f3\u304c\u30ab\u30d3\u304b\u3089\u767a\u898b\u3055\u308c\u305f\u3088\u3046\u306b\u3001\u6cbb\u7642\u85ac\u958b\u767a\u306e\u305f\u3081\u306b\u6570\u591a\u304f\u306e\u30ab\u30d3\u306e\u57f9\u990a\u304b\u3089\u6cbb\u7642\u85ac\u306e\u62bd\u51fa\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3053\u3067\u3001\u6ce8\u76ee\u3055\u308c\u305f\u306e\u304c\u5316\u5408\u7269\u306e\uff11\u3064\u304c\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u300d\u3002\u3082\u3068\u3082\u3068\u306f1932\u5e74\u306b\u5831\u544a\u3055\u308c\u305f\u5316\u5408\u7269\u3067\u3059\u304c\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u306f\u30af\u30ed\u30ed\u30ad\u30f3\u8010\u6027\u306e\u30de\u30e9\u30ea\u30a2\u539f\u866b\u30d7\u30e9\u30b9\u30e2\u30b8\u30a6\u30e0\u30fb\u30d5\u30a1\u30eb\u30b7\u30d1\u30eb\u30e0K1\u682a\u306b\u5bfe\u3057\u3066\u975e\u5e38\u306b\u5f37\u3044\u6297\u30de\u30e9\u30ea\u30a2\u6d3b\u6027\u3092\u793a\u3057\u305f\u3053\u3068\u304b\u3089\u3001\u6ce8\u76ee\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.nature.com\/articles\/ja2010124#Sch1\" target=\"_blank\" rel=\"noreferrer noopener\">In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A\u2013C, produced by Penicillium sp. FKI-4410<\/a>\uff09<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%AE%E6%AF%92%E6%80%A7%E3%81%AF%EF%BC%9F\"><\/span>\u30d7\u30d9\u30eb\u30eb\u9178\u306e\u6bd2\u6027\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T072111.648.webp\" alt=\"\" class=\"wp-image-7386 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T072111.648.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T072111.648-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T072111.648-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306b\u6297\u30de\u30e9\u30ea\u30a2\u6d3b\u6027\u3068\u3057\u3066\u811a\u5149\u3092\u6d74\u3073\u305f\u30d7\u30d9\u30eb\u30eb\u9178\u3067\u3059\u304c\u3001\u5927\u304d\u306a\u554f\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b9f\u969b\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u76ae\u4e0b\u6295\u4e0e\u306b\u3088\u308b\u30de\u30a6\u30b9\u306e\u5b9f\u9a13\u3067\u306f5 mg\/kg \u00d7 2(0\u65e5\u76ee\u30681\u65e5\u76ee\uff09\u306e\u6295\u4e0e\u3067\u30015\u5339\u4e2d 4\u5339\u304c 3\u65e5\u76ee\u307e\u3067\u306b\u6b7b\u4ea1\u3059\u308b<\/mark><\/strong>\u3068\u3044\u3046\u5f37\u3044\u6bd2\u6027\u304c\u3042\u3063\u305f\u306e\u3067\u3059\u3002\u3057\u304b\u3082\u7d4c\u53e3\u6295\u4e0e\u3067\u306f\u30d7\u30d9\u30eb\u30eb\u9178\u306f\u6297\u30de\u30e9\u30ea\u30a2\u6d3b\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3053\u3067\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u3092\u3082\u3068\u306b\u69d8\u3005\u306a\u5316\u5408\u7269\u304c\u6a21\u7d22\u3055\u308c\u307e\u3057\u305f\u3002\u4f8b\u3048\u3070\u3001\u300c\u30c8\u30ed\u30dd\u30f3\u300d\u300c\u30c8\u30ed\u30dd\u30ed\u30f3\u300d\u300c\u30d2\u30ce\u30ad\u30c1\u30aa\u30fc\u30eb\u300d\u300c7-\u30d2\u30c9\u30ed\u30ad\u30b7\u30c8\u30ed\u30dd\u30ed\u30f3\u300d\u306a\u3069\u3067\u3059\u306d\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306b\u3001\u30af\u30ed\u30ed\u30ad\u30f3\u8010\u6027\u30de\u30e9\u30ea\u30a2\u3078\u306e\u6cbb\u7642\u85ac\u7814\u7a76\u306e\u790e\u3068\u3057\u3066\u6d3b\u8e8d\u3057\u305f\u7269\u8cea\u304c\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u300d\u3060\u3063\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uff08\u53c2\u7167\uff1a<a rel=\"noreferrer noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/ja2010124\">In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A\u2013C, produced by Penicillium sp. FKI-4410<\/a>\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uff08\u53c2\u7167\uff1a<a rel=\"noreferrer noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41598-017-07718-3\">Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies<\/a>\uff09<\/p>\n\n\n<ins class=\"adsbygoogle\"\n        style=\"display:block; text-align:center;\"\n        data-ad-layout=\"in-article\"\n        data-ad-format=\"fluid\"\n        data-ad-client=\"ca-pub-5748007460615735\"\n        data-ad-slot=\"4711491386\"><\/ins>\n        <script>\n        (adsbygoogle = window.adsbygoogle || []).push({});\n        <\/script>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%97%E3%83%99%E3%83%AB%E3%83%AB%E9%85%B8%E3%81%A8%E7%B4%85%E9%BA%B9%E3%82%B5%E3%83%97%E3%83%AA%E3%83%A1%E3%83%B3%E3%83%88%E3%81%A8%E3%81%AE%E9%96%A2%E4%BF%82%E3%81%AF%EF%BC%9F\"><\/span>\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u306e\u95a2\u4fc2\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T073347.774.webp\" alt=\"\" class=\"wp-image-7388 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T073347.774.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T073347.774-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/04\/image-2024-04-01T073347.774-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u306f\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u306f\u95a2\u4fc2\u306f\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u7d50\u8ad6\u304b\u3089\u3044\u3046\u3068\u300c<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u95a2\u9023\u6027\u306f\uff08\u672c\u6765\u306f\uff09\u975e\u5e38\u306b\u8584\u3044<\/mark><\/strong>\u300d\u3068\u8a00\u3048\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306f\u4ee5\u4e0b\u306e\uff12\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460\u3000\u7d05\u9eb9\u3068\u30d7\u30d9\u30eb\u30eb\u9178\u306e\u57f9\u990a\u904e\u7a0b\u306f\u5927\u304d\u304f\u9055\u3046<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305a\u3001\u7d05\u9eb9\u306e\u4f5c\u308a\u65b9\u306f\u975e\u5e38\u306b\u30c7\u30ea\u30b1\u30fc\u30c8\u3067\u3059\u3002\u5b9f\u969b\u3001\u300c\u7a2e\u9eb9\u300d\u3068\u300c\u88fd\u9eb9\u300d\u306e\uff12\u6bb5\u968e\u3092\u7d4c\u3066\u7d05\u9eb9\u7c73\u306f\u4f5c\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u3010\u7a2e\u9eb9\u306e\u4f5c\u6210\u3011<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u3046\u308b\u3061\u7c73\u309218\u6642\u9593\u6c34\u306b\u6d78\u3059\u3002<\/li>\n\n\n\n<li>\u80de\u5b50\u3092\u7121\u83cc\u7684\u306b\u63a5\u7a2e\u305732\u5ea67\u65e5\u57f9\u990a\u3057\u3066\u3001\u5341\u5206\u306b\u80de\u5b50\u3092\u7740\u751f\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li>\u708a\u98ef\u7c73\u3068\u6c34\u3092\u7121\u83cc\u7684\u306b\u6dfb\u52a0\u3057\u3066\u300132\u5ea6\u30017\u65e5\u9593\u57f9\u990a\u3057\u3066\u7121\u83cc\u7684\u306b\u300c\u7a2e\u9eb9\u300d\u3092\u4f5c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u3010\u88fd\u9eb9\u306e\u4f5c\u6210\u3011<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u3046\u308b\u3061\u7c73\u309218\u6642\u9593\u6c34\u306b\u6d78\u3057\u3066\u300160\u5206\u84b8\u3057\u716e\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u84b8\u7c73\uff0824\uff5e\uff13\uff17\u5ea6\uff09\u3092\u9eb9\u7aaf\u306b\u3044\u308c\u3001\u7a2e\u9eb9\uff086\uff05\uff09\u3092\u63a5\u7a2e\u6df7\u548c\u3057\u305f\u306e\u3061\u300132\u5ea6\u3067\u88fd\u9eb9\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u9014\u4e2d\u767a\u9175\u306b\u3088\u308b\u6e29\u5ea6\u4e0a\u6607\u304c\u3042\u308b\u305f\u3081\u3001\u300c\u624b\u5165\u308c\u300d\u3092\u884c\u304438\u5ea6\u4ee5\u4e0b\u306b\u4e0b\u3052\u308b\u5fc5\u8981\u304c\u3042\u308b\u3053\u3068\u3084\u3001\u767a\u9175\u306e\u904e\u7a0b\u3067\u6c34\u5206\u91cf\u3082\u3078\u308b\u305f\u3081\u3001\u6c34\u5206\u3092\u9069\u5b9c\u88dc\u7d66\u3059\u308b\u3088\u3046\u306b\u3059\u308b<\/li>\n\n\n\n<li>\u4ee5\u4e0a\u306e\u5de5\u7a0b\u30926\uff5e7\u65e5\u9593\u304b\u3051\u3066\u884c\u3046\u3002<\/li>\n<\/ul>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u5b9f\u969b\u3001\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3082\u306e\u3059\u3054\u3044\u7a2e\u985e\u306e\u5316\u5408\u7269\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u30e2\u30ca\u30b3\u30ea\u30f3\u3001\u8272\u7d20 \u3001\u6709\u6a5f\u9178 \u3001\u30a2\u30df\u30ce\u9178 \u3001\u30b9\u30c6\u30ed\u30fc\u30eb \u3001\u30c7\u30ab\u30ea\u30f3\u8a98\u5c0e\u4f53\u3001\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u3001\u30ea\u30b0\u30ca\u30f3\u3001\u30af\u30de\u30ea\u30f3\u3001\u30c6\u30eb\u30da\u30ce\u30a4\u30c9\u306a\u3069\u305d\u306e\u6570\u306f100\u7a2e\u985e\u306b\u8feb\u308b\u52e2\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u6210\u5206\u306f\u5168\u3066\u540c\u5b9a\u3055\u308c\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u305d\u306e\u4e2d\u306b\u306f\u30d7\u30d9\u30eb\u30eb\u9178\u306f\u542b\u307e\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.frontiersin.org\/journals\/pharmacology\/articles\/10.3389\/fphar.2019.01449\/full\" target=\"_blank\" rel=\"noreferrer noopener\">Red Yeast Rice: A Systematic Review of the Traditional Uses, Chemistry, Pharmacology, and Quality Control of an Important Chinese Folk Medicine\uff09<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462\u3000\u30d7\u30d9\u30eb\u30eb\u9178\u3060\u3051\u3092\u5206\u96e2\u3059\u308b\u306e\u306b\u306f\u591a\u304f\u306e\u5de5\u7a0b\u304c\u5fc5\u8981<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3082\u3046\uff11\u3064\u306e\u7406\u7531\u3068\u3057\u3066\u306f\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u3060\u3051\u3092\u5206\u96e2\u3059\u308b\u306e\u306b\u306f\u591a\u304f\u306e\u5de5\u7a0b\u304c\u5fc5\u8981\u3068\u3044\u3046\u306e\u304c\u3042\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u300cFKI-4410\u300d\u3068\u3044\u3046\u30ab\u30d3\u304c\u305f\u307e\u305f\u307e\u7d05\u9eb9\u306e\u88fd\u9020\u3067\u6df7\u5165\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u30ab\u30d3\u304b\u3089\u3044\u304d\u306a\u308a\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u3060\u3051\u300d\u304c\u7523\u751f\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5b9f\u969b\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u3092\u5206\u96e2\u30fb\u62bd\u51fa\u3057\u305f\u8ad6\u6587\u306b\u3088\u308b\u3068\u3001\u30d6\u30da\u30eb\u30eb\u9178\u306e\u7cbe\u88fd\u306e\u305f\u3081\u306b\u4ee5\u4e0b\u306e\u5de5\u7a0b\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>10\u65e5\u9593\u57f9\u990a\u3057\u305f\u30ab\u30d3\u306e\u57f9\u990a\u6db2\u3092\u9060\u5fc3\u5206\u96e2\u3002<\/li>\n\n\n\n<li>\u4e0a\u6f84\u307f\u3092\u7279\u5b9a\u306e\u30ab\u30e9\u30e0\u306b\u901a\u3057\u30010.1% TFA\u6c34\u6eb6\u6db2\u3067\u5e73\u8861\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li>40%\u30e1\u30bf\u30ce\u30fc\u30eb\u6c34\u6eb6\u6db2\u3067\u6d17\u6d44\u5f8c\u3001100%\u30e1\u30bf\u30ce\u30fc\u30eb\u6c34\u6eb6\u6db2\u3067\u6709\u52b9\u6210\u5206\u3092\u6eb6\u51fa\u3002<\/li>\n\n\n\n<li>\u6eb6\u51fa\u6db2\u3092\u771f\u7a7a\u4e0b\u3067\u6fc3\u7e2e\u3057\u3001\u7a92\u7d20\u30ac\u30b9\u3067\u4e7e\u71e5\u3002<\/li>\n\n\n\n<li>\u5f97\u3089\u308c\u305f\u7269\u8cea\u3092TFA\u6c34\u6eb6\u6db2\u3067\u6eb6\u89e3\u3057\u3001\u5225\u306e\u30ab\u30e9\u30e0\u3067\u7cbe\u88fd\u3002<\/li>\n\n\n\n<li>\u7cbe\u88fd\u5f8c\u306e\u6eb6\u6db2\u309210%\u30a2\u30bb\u30c8\u30cb\u30c8\u30ea\u30eb\u6c34\u6eb6\u6db2\u3067\u5206\u753b\u3057\u3001\u7d50\u6676\u3092\u4f5c\u6210\u3002<\/li>\n\n\n\n<li>\u7d50\u6676\u3092HPLC\u3067\u66f4\u306b\u7cbe\u88fd\u3057\u3066\u30d7\u30d9\u30eb\u30eb\u9178\u3092\u5206\u96e2\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306b\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u3060\u3051\u3092\u53d6\u308a\u51fa\u3059\u300d\u3068\u3044\u3046\u306e\u306f\u3082\u306e\u3059\u3054\u3044\u52b4\u529b\u304c\u5fc5\u8981\u306a\u306e\u3067\u3059\u306d\u3002\u3057\u305f\u304c\u3063\u3066\u3001\uff08\u3082\u3061\u308d\u3093\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u88fd\u9020\u306b\u95a2\u308f\u3063\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\uff09<strong>\u30d7\u30d9\u30eb\u30eb\u9178\u3068\u7d05\u9eb9\u306e\u88fd\u9020\u904e\u7a0b\u306f\u975e\u5e38\u306b\u95a2\u9023\u6027\u304c\u8584\u3044<\/strong>\u3053\u3068\u304c\u3046\u304b\u304c\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.nature.com\/articles\/ja2010124\" target=\"_blank\" rel=\"noreferrer noopener\">In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A\u2013C, produced by Penicillium sp. FKI-4410<\/a>\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0a\u8a18\u306e\u3088\u3046\u306b\u8003\u3048\u308b\u3068\u3001\u5c0f\u6797\u88fd\u85ac\u306e\u7d05\u9eb9\u554f\u984c\u306e\u4ef6\u306f\u3001\u4eca\u307e\u3067\u306e\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u554f\u984c\u3068\u306f\u9055\u3063\u305f\u5074\u9762\u304c\u3042\u308a\u305d\u3046\u3067\u3059\u306d\u3002\u771f\u76f8\u304c\u4e00\u523b\u3082\u65e9\u304f\u89e3\u660e\u3055\u308c\u308b\u3053\u3068\u3092\u5fc3\u3088\u308a\u9858\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3010\u3053\u306e\u8a18\u4e8b\u3092\u66f8\u3044\u305f\u4eba\u3011\u3000<br>\u4e00\u4e4b\u6c5f\u99c5\u524d\u3072\u307e\u308f\u308a\u533b\u9662\u9662\u9577\u306e\u4f0a\u85e4\u5927\u4ecb\u3068\u7533\u3057\u307e\u3059\u3002<strong><a href=\"https:\/\/www.soujinkai.or.jp\/himawariNaiHifu\/doctors\/\">\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u306f\u3053\u3061\u3089<\/a><\/strong>\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%81%82%E3%82%8F%E3%81%9B%E3%81%A6%E3%81%93%E3%81%A1%E3%82%89%E3%82%82%E3%82%AA%E3%82%B9%E3%82%B9%E3%83%A1%E3%81%A7%E3%81%99\"><\/span>\u3042\u308f\u305b\u3066\u3053\u3061\u3089\u3082\u30aa\u30b9\u30b9\u30e1\u3067\u3059<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/red-yeast-rice\/\" title=\"\">\u7d05\u9eb9\u3068\u306f\uff1f\u7d05\u9eb9\u306e\u52b9\u679c\u3068\u5371\u967a\u6027\u306b\u3064\u3044\u3066\u3010\u81ea\u4e3b\u56de\u53ce\u3011<\/a><\/strong><\/li>\n\n\n\n<li><strong><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/mycotoxin\/\">\u5c0f\u9ea6\u306a\u3069\u306b\u6f5c\u3080\u300c\u30ab\u30d3\u6bd2\u300d\u306e\u75c7\u72b6\u3068\u5bfe\u7b56\u306b\u3064\u3044\u3066\u3010\u30a2\u30d5\u30e9\u30c8\u30ad\u30b7\u30f3\u30fb\u767a\u304c\u3093\u6027\u3011<\/a><\/strong>\u3082<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/liver-function\/\">\u3010AST\u30fbALT\u30fb\u03b3-GTP\u3011\u809d\u81d3\u306e\u6570\u5024\u304c\u60aa\u3044\u3068\u3044\u308f\u308c\u305f\u3089\uff1f\u809d\u6a5f\u80fd\u306e\u6570\u5024\u3092\u4e0b\u3052\u308b\u65b9\u6cd5\u3082\u89e3\u8aac<\/a><\/strong><\/li>\n\n\n\n<li><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/kidney-food\/\"><strong>\u3010\u533b\u5e2b\u304c\u89e3\u8aac\u3011\u814e\u81d3\u306b\u3044\u3044\u98df\u3079\u7269\u3068\u60aa\u3044\u98df\u3079\u7269\u306b\u3064\u3044\u3066<\/strong><\/a><\/li>\n\n\n\n<li><strong><a href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/creatinine\/\">\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3068\u306f\uff1f\u6570\u5024\u304c\u9ad8\u3044\u539f\u56e0\u3068\u4e0b\u3052\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066<\/a><\/strong><\/li>\n<\/ul>\n\n\n<ins class=\"adsbygoogle\"\n        style=\"display:block; text-align:center;\"\n        data-ad-layout=\"in-article\"\n        data-ad-format=\"fluid\"\n        data-ad-client=\"ca-pub-5748007460615735\"\n        data-ad-slot=\"4711491386\"><\/ins>\n        <script>\n        (adsbygoogle = window.adsbygoogle || []).push({});\n        <\/script>\n","protected":false},"excerpt":{"rendered":"\u5c0f\u6797\u88fd\u85ac\u306e\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u691c\u51fa\u3055\u308c\u305f\u3068\u3055\u308c\u308b\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u300d\u3002\u307f\u306a\u3055\u3093\u3082\u805e\u3044\u305f\u3053\u3068\u304c\u306a\u3044\u6210\u5206\u3067\u30d3\u30c3\u30af\u30ea\u3057\u305f\u3053\u3068\u3067\u3057\u3087\u3046\u3002 \u4eca\u56de\u3001\u30d7\u30d9\u30eb\u30eb\u9178\u306b\u3064\u3044\u3066 \u3092\u542b\u3081\u3066\u3001\u69d8\u3005\u306a\u8ad6\u6587\u304b\u3089\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002 \u7d05\u9eb9\u3084\u7d05\u9eb9\u30b5\u30d7\u30ea [&hellip;]","protected":false},"author":4,"featured_media":7393,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,77,66],"tags":[],"class_list":["post-7382","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-internal-medicine","category-77","category-66"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"\u5c0f\u6797\u88fd\u85ac\u306e\u7d05\u9eb9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u691c\u51fa\u3055\u308c\u305f\u3068\u3055\u308c\u308b\u300c\u30d7\u30d9\u30eb\u30eb\u9178\u300d\u3002\u307f\u306a\u3055\u3093\u3082\u805e\u3044\u305f\u3053\u3068\u304c\u306a\u3044\u6210\u5206\u3067\u30d3\u30c3\u30af\u30ea\u3057\u305f\u3053\u3068\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Daisuke Ito\"\/>\n\t<link rel=\"canonical\" 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