{"id":7862,"date":"2024-10-02T09:40:21","date_gmt":"2024-10-02T00:40:21","guid":{"rendered":"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/?p=7862"},"modified":"2024-10-30T06:12:03","modified_gmt":"2024-10-29T21:12:03","slug":"replicon-vaccine","status":"publish","type":"post","link":"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/","title":{"rendered":"\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u3010\u4ed5\u7d44\u307f\u30fb\u304a\u65ad\u308a\u30fb\u6cbb\u9a13\u3011"},"content":{"rendered":"\n<p>10\u6708\u3088\u308a\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u304c\u958b\u59cb\u306b\u306a\u308a\u307e\u3059\u306d\u3002\u65e5\u672c\u3067\u306f\u4ee5\u4e0b\u306e5\u7a2e\u985e\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3068\u3057\u3066\u8a8d\u53ef\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u306emRNA\u30ef\u30af\u30c1\u30f3\u3067\u3042\u308b\u300c\u30b3\u30df\u30ca\u30c6\u30a3\u300d<\/li>\n\n\n\n<li>\u30e2\u30c7\u30eb\u30ca\u793e\u306emRNA\u30ef\u30af\u30c1\u30f3\u300c\u30b9\u30d1\u30a4\u30af\u30d0\u30c3\u30af\u30b9\u300d<\/li>\n\n\n\n<li>\u7b2c\u4e00\u4e09\u5171\u306emRNA\u30ef\u30af\u30c1\u30f3\u300c\u30c0\u30a4\u30c1\u30ed\u30ca\u300d<\/li>\n\n\n\n<li>\u6b66\u7530\u85ac\u54c1\u306e\u7d44\u307f\u63db\u3048\u30bf\u30f3\u30d1\u30af\u30ef\u30af\u30c1\u30f3\u300c\u30cc\u30d0\u30ad\u30bd\u30d3\u30c3\u30c9\u300d<\/li>\n\n\n\n<li>Meiji Seika \u30d5\u30a1\u30eb\u30de\u306e\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u300c\u30b3\u30b9\u30bf\u30a4\u30d9\u300d<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u3046\u3061\u6700\u3082\u4e16\u9593\u3092\u9a12\u304c\u305b\u3066\u3044\u308b\u30ef\u30af\u30c1\u30f3\u304c\u3001\u6b21\u4e16\u4ee3mRNA\u30ef\u30af\u30c1\u30f3\u3068\u3082\u547c\u3070\u308c\u308b\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>mRNA\u30ef\u30af\u30c1\u30f3\u3092\u3055\u3089\u306b\u6539\u826f\u3057\u305f\u30ef\u30af\u30c1\u30f3\u3067\u3042\u308b<\/li>\n\n\n\n<li>\u65e5\u672c\u3060\u3051\u3057\u304b\u8a8d\u53ef\u304c\u3055\u308c\u3066\u3044\u306a\u3044<\/li>\n<\/ul>\n\n\n\n<p>\u3044\u3063\u305f\u7406\u7531\u304b\u3089\u591a\u6570\u306e\u30e1\u30c7\u30a3\u30a2\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3001SNS\u3067\u306f\u591a\u304f\u306e\u975e\u96e3\u304c\u6d74\u3073\u305b\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4e2d\u306b\u306f\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3063\u305f\u4eba\u306f\u5165\u5e97\u3092\u304a\u65ad\u308a\u3057\u307e\u3059\u300d\u3068\u3044\u3046\u304a\u5e97\u3082\u51fa\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u305d\u308c\u3092\u5b9f\u8a3c\u3055\u308c\u305f\u8ad6\u6587\u304b\u3089\u79d1\u5b66\u7684\u306b\u7d10\u89e3\u3044\u305f\u60c5\u5831\u306f\u306a\u304b\u306a\u304b\u5c11\u306a\u3044\u3068\u611f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u3067\u4eca\u56de\u306f\u306a\u308b\u3079\u304f\u5ba2\u89b3\u7684\u306a\u7acb\u5834\u304b\u3089<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3068\u306f\u3069\u3093\u306a\u30ef\u30af\u30c1\u30f3\u306a\u306e\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u5b89\u5168\u6027\u306f\u672c\u5f53\u306f\u3069\u3046\u306a\u306e\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3067\u5642\u3055\u308c\u3066\u3044\u308b\u300c\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u300d\u306f\u8d77\u3053\u308b\u306e\u304b<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u306a\u3069\u306b\u3064\u3044\u3066\u3001\u6cbb\u9a13\u3084\u8ad6\u6587\u306e\u30c7\u30fc\u30bf\u306a\u3069\u3092\u3082\u3068\u306b\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u52d5\u753b\u3067\u3082\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u307e\u3057\u305f\u306e\u3067\u3001\u4f75\u305b\u3066\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/mark><\/strong><\/p>\n\n\n<ins class=\"adsbygoogle\"\n        style=\"display:block; text-align:center;\"\n        data-ad-layout=\"in-article\"\n        data-ad-format=\"fluid\"\n        data-ad-client=\"ca-pub-5748007460615735\"\n        data-ad-slot=\"4711491386\"><\/ins>\n        <script>\n        (adsbygoogle = window.adsbygoogle || []).push({});\n        <\/script>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #4bd151;color:#4bd151\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #4bd151;color:#4bd151\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%81%AE%E4%BB%95%E7%B5%84%E3%81%BF%E3%81%AF%EF%BC%9F\" >\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u4ed5\u7d44\u307f\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%82%92%E3%81%86%E3%81%A4%E3%83%A1%E3%83%AA%E3%83%83%E3%83%88%E3%81%AF%EF%BC%9F\" >\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u3046\u3064\u30e1\u30ea\u30c3\u30c8\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%81%AE%E5%AE%89%E5%85%A8%E6%80%A7%E3%82%84%E5%89%AF%E4%BD%9C%E7%94%A8%E3%81%AF%EF%BC%9F\" >\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u5b89\u5168\u6027\u3084\u526f\u4f5c\u7528\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%82%92%E6%89%93%E3%81%A4%E3%81%A8%E5%85%A5%E5%BA%97%E3%81%8A%E6%96%AD%E3%82%8A%E3%80%81%E3%81%AF%E6%AD%A3%E3%81%97%E3%81%84%E3%81%AE%E3%81%8B%EF%BC%9F\" >\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3064\u3068\u5165\u5e97\u304a\u65ad\u308a\u3001\u306f\u6b63\u3057\u3044\u306e\u304b\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E5%BD%93%E9%99%A2%E3%81%A7%E3%81%AF%E3%80%8C%E3%83%95%E3%82%A1%E3%82%A4%E3%82%B6%E3%83%BC%E7%A4%BE%E8%A3%BD%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%80%8D%E3%82%92%E6%8E%A1%E7%94%A8%E3%81%97%E3%81%A6%E3%81%84%E3%81%BE%E3%81%99\" >\u5f53\u9662\u3067\u306f\u300c\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u88fd\u30ef\u30af\u30c1\u30f3\u300d\u3092\u63a1\u7528\u3057\u3066\u3044\u307e\u3059<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6%E3%80%81%E5%8B%95%E7%94%BB%E3%81%A7%E3%82%82%E3%82%8F%E3%81%8B%E3%82%8A%E3%82%84%E3%81%99%E3%81%8F%E8%A7%A3%E8%AA%AC%E3%81%97%E3%81%A6%E3%81%84%E3%81%BE%E3%81%99\" >\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u3001\u52d5\u753b\u3067\u3082\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/replicon-vaccine\/#%E3%81%82%E3%82%8F%E3%81%9B%E3%81%A6%E3%81%93%E3%81%A1%E3%82%89%E3%82%82%E3%82%AA%E3%82%B9%E3%82%B9%E3%83%A1%E3%81%A7%E3%81%99\" >\u3042\u308f\u305b\u3066\u3053\u3061\u3089\u3082\u30aa\u30b9\u30b9\u30e1\u3067\u3059<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%81%AE%E4%BB%95%E7%B5%84%E3%81%BF%E3%81%AF%EF%BC%9F\"><\/span>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u4ed5\u7d44\u307f\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-900x675.png\" alt=\"\" class=\"wp-image-7865 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-900x675.png 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-300x225.png 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-768x576.png 768w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8.png 1024w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3068\u306f\u3001\u5c11\u306a\u3044\u6709\u52b9\u6210\u5206\u91cf\u3067\u52b9\u679c\u304c\u9577\u304f\u7d9a\u304f\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u300c\u6b21\u4e16\u4ee3mRNA\u30ef\u30af\u30c1\u30f3\u300d\u3068\u547c\u3070\u308c\u308b\u30ef\u30af\u30c1\u30f3\u3067\u3059\u3002\u305d\u306e\u6700\u5927\u306e\u7279\u5fb4\u306fmRNA\u304c\u81ea\u5206\u81ea\u8eab\u3067\u8907\u88fd\u3055\u308c\u308b\u3053\u3068\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306f\u6295\u4e0e\u3055\u308c\u308b\u3068\u7d30\u80de\u5185\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3001\u5927\u91cf\u306b\u8907\u88fd\u3059\u308b\u305f\u3081\u306e<strong>\u30ec\u30d7\u30ea\u30ab\u30fc\u30bc<\/strong>\u3068\u3044\u3046\u9175\u7d20\u3092\u4f5c\u308c\u308b\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\uff08mRNA\uff09\u3092\u9001\u308a\u8fbc\u307f\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3057\u3066\u3001\u30ec\u30d7\u30ea\u30ab\u30fc\u30bc\u304cmRNA\u3092\u5897\u5e45\u3059\u308b\u3053\u3068\u3067\u3001\u52b9\u7387\u7684\u306b\u30a6\u30a4\u30eb\u30b9\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u751f\u6210\u3055\u308c\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30d4\u30fc\u6a5f\u3067\u4f8b\u3048\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u5f93\u6765\u306emRNA\u30ef\u30af\u30c1\u30f3\u306f\u3001\u4e00\u679a\u4e00\u679a\u624b\u66f8\u304d\u3067\u30c1\u30e9\u30b7\u3092\u4f5c\u308b\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002\u4e00\u679a\u4e00\u679a\u4e01\u5be7\u306b\u4f5c\u308b\u306e\u3067\u3001\u52b9\u679c\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u4f5c\u308b\u306e\u306b\u6642\u9593\u304c\u304b\u304b\u308a\u307e\u3059\u3057\u3001\u305f\u304f\u3055\u3093\u306e\u30c1\u30e9\u30b7\u3092\u4f5c\u308b\u306e\u306f\u5927\u5909\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306f\u3001\u30b3\u30d4\u30fc\u6a5f\u3092\u4f7f\u3063\u3066\u30c1\u30e9\u30b7\u3092\u5927\u91cf\u306b\u4f5c\u308b\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002\u30b3\u30d4\u30fc\u6a5f\u306b\u306f\u3001\u30c1\u30e9\u30b7\u306e\u5143\u3068\u306a\u308b\u539f\u7a3f\u3068\u3001\u305d\u308c\u3092\u30b3\u30d4\u30fc\u3059\u308b\u305f\u3081\u306e\u6a5f\u80fd\u304c\u5099\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u539f\u7a3f\u306b\u3042\u305f\u308b\u306e\u304c\u30a6\u30a4\u30eb\u30b9\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u308b\u8a2d\u8a08\u56f3\uff08mRNA\uff09\u3067\u3001\u30b3\u30d4\u30fc\u6a5f\u80fd\u306b\u3042\u305f\u308b\u306e\u304c\u30ec\u30d7\u30ea\u30ab\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3059\u308b\u3068\u3001\u7d30\u80de\u306e\u4e2d\u306b\u30b3\u30d4\u30fc\u6a5f\uff08\u30ec\u30d7\u30ea\u30ab\u30fc\u30bc\uff09\u3068\u30c1\u30e9\u30b7\u306e\u539f\u7a3f\uff08mRNA\uff09\u304c\u9001\u308a\u8fbc\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3059\u308b\u3068\u3001\u30b3\u30d4\u30fc\u6a5f\u304c\u539f\u7a3f\u3092\u3069\u3093\u3069\u3093\u30b3\u30d4\u30fc\u3057\u59cb\u3081\u3001\u5927\u91cf\u306e\u30c1\u30e9\u30b7\uff08\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u304c\u4f5c\u3089\u308c\u308b\u30fb\u30fb\u30fb\u3068\u3044\u3046\u308f\u3051\u3067\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u672c\u6765\u30a6\u30a4\u30eb\u30b9\u304c\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b\u969b\u306b\u4f7f\u3046\u3082\u306e\u3067\u3059\u304c\u3001\u30ef\u30af\u30c1\u30f3\u3067\u306f\u305d\u308c\u304c\u5358\u72ec\u3067\u5b58\u5728\u3059\u308b\u305f\u3081\u3001\u5358\u4f53\u3067\u91cd\u7be4\u306a\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u306f\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u81ea\u8eab\u3082\u7d4c\u904e\u3068\u3068\u3082\u306b\u306a\u304f\u306a\u308b\u306e\u3067\u300c\u305a\u3063\u3068\u6b8b\u308a\u7d9a\u3051\u308b\u300d\u3068\u3044\u3046\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u3001\u81e8\u5e8a\u8a66\u9a13\u3092\u884c\u3046\u524d\u6bb5\u968e\u306e\u5b9f\u9a13\u3067\u3001\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u3084\u30d2\u30c8\u306e\u76ae\u819a\u7d30\u80de\u304b\u3089\u306e\u975e\u81e8\u5e8a\u8a66\u9a13\u3088\u308a\u3001\u7523\u751f\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001<strong>\u7b4b\u8089\u5185\u3067\u304a\u304a\u3080\u306d7\uff5e 8\u65e5\u76ee\u307e\u3067\u5897\u52a0\u3057\u3001\u305d\u306e\u5f8c\u6642\u9593\u306e\u7d4c\u904e\u3068\u3068\u3082\u306b\u6e1b\u5c11\u3057\u300121\u65e5\u76ee\u306b\u6d88\u5931\u3059\u308b<\/strong>\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f21\u65e5\u76ee\u304f\u3089\u3044\u306b\u6d88\u5931\u3059\u308b\u3053\u3068\u3092\u4eba\u306e\u76ae\u819a\u7d44\u7e54\u306b\u5165\u308c\u305f\u5834\u5408\u3067\u3082\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3088\u3063\u3066\u8907\u88fd\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u3001\u4f53\u5185\u306e\u514d\u75ab\u7cfb\u306f\u300c\u7570\u7269\u300d\u3068\u8a8d\u8b58\u3057\u3066\u3001\u305d\u308c\u306b\u5bfe\u3059\u308b\u6297\u4f53\u3084\u7d30\u80de\u6027\u514d\u75ab\u3092\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u5b9f\u969b\u306b\u30a6\u30a4\u30eb\u30b9\u306b\u611f\u67d3\u3057\u305f\u969b\u306b\u3001\u514d\u75ab\u7cfb\u304c\u8fc5\u901f\u306b\u53cd\u5fdc\u3057\u3001\u30a6\u30a4\u30eb\u30b9\u3092\u6392\u9664\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u308f\u3051\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u3068\u3081\u308b\u3068\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u300c\u30b3\u30d4\u30fc\u80fd\u529b\u300d\u3092\u5fdc\u7528\u3057\u3001\u52b9\u7387\u7684\u306b\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u8a13\u7df4\u3059\u308b\u3053\u3068\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3059\u308b\u9632\u5fa1\u52b9\u679c\u3092\u9ad8\u3081\u308b\u30ef\u30af\u30c1\u30f3\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>(\u53c2\u7167\uff1a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31472371\/\" target=\"_blank\" rel=\"noreferrer noopener\">Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8759012\/\" target=\"_blank\" rel=\"noreferrer noopener\">Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial<\/a>\uff09<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%82%92%E3%81%86%E3%81%A4%E3%83%A1%E3%83%AA%E3%83%83%E3%83%88%E3%81%AF%EF%BC%9F\"><\/span>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u3046\u3064\u30e1\u30ea\u30c3\u30c8\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3.webp\" alt=\"\" class=\"wp-image-7866 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u30e1\u30ea\u30c3\u30c8\u3092\u307e\u3068\u3081\u308b\u306a\u3089\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u52b9\u679c\u306e\u6301\u7d9a\u671f\u9593\u304c\u9577\u3044<\/strong><\/li>\n\n\n\n<li><strong>\u5c11\u306a\u3044\u6295\u4e0e\u91cf\u3067\u6e08\u3080<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u306e2\u3064\u306b\u96c6\u7d04\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u4eba\u6210\u4eba828\u540d\u306b\u5bfe\u3057\u3066\u3001\u4eca\u56de\u306e\u30b3\u30b9\u30bf\u30a4\u30d9\uff08ARCT-154\uff09\u3068\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u30ef\u30af\u30c1\u30f3\uff08\u30b3\u30df\u30ca\u30c6\u30a3\uff09\u3092\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u884c\u3063\u305f\u8ad6\u6587\u306b\u3088\u308b\u3068\u3001\u30aa\u30df\u30af\u30ed\u30f3BA.4\/5\u682a\u306b\u5bfe\u3057\u3066\u306e\u4e2d\u548c\u6297\u4f53\u4fa1\u306f<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6295\u4e0e\u5f8c30\u65e5<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d92125\u3001\u30b3\u30df\u30ca\u30c6\u30a31624\uff081.31\u500d\uff09<\/li>\n\n\n\n<li><strong>\u6295\u4e0e\u5f8c90\u65e5<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d91892\u3001\u30b3\u30df\u30ca\u30c6\u30a3888\uff082.13\u500d\uff09<\/li>\n\n\n\n<li><strong>\u6295\u4e0e\u5f8c180\u65e5<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d91119\u3001\u30b3\u30df\u30ca\u30c6\u30a3495\uff082.26\u500d\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u3068\u30b3\u30b9\u30bf\u30a4\u30d9\u306e\u65b9\u304c\u5897\u52a0\u3057\u3001\u304b\u3064\u4e2d\u548c\u6297\u4f53\u4fa1\u304c6\u30ab\u6708\u306b\u308f\u305f\u3063\u3066\u9577\u304f\u7d9a\u304f\u3053\u3068\u304c\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30b9\u30bf\u30a4\u30d9\u306f5\u03bcg\u306emRNA\u3092\u542b\u3080\u306e\u306b\u5bfe\u3057\u3001\u30b3\u30df\u30ca\u30c6\u30a3\u306f30\u03bcg\u3068\u3001\u30b3\u30b9\u30bf\u30a4\u30d9\u306f\u30b3\u30df\u30ca\u30c6\u30a3\u306e\u7d046\u5206\u306e\uff11mRNA\u91cf\u3067\u3042\u308b\u306b\u3082\u95a2\u308f\u3089\u305a\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u72ec\u7279\u306e\u300c\u81ea\u5df1\u5897\u6b96\u578b\u300d\u306e\u6027\u8cea\u306b\u3088\u308a\u300121\u65e5\u307e\u3067\u6d88\u5931\u3059\u308b\u307e\u3067\u306e\u9593\u306b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5897\u6b96\u3055\u308c\u3001\u3088\u308a\u591a\u304f\u306e\u514d\u75ab\u5fdc\u7b54\u304c\u8d77\u3053\u3063\u305f\u305f\u3081\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4ed6\u306b\u3082\u30d9\u30c8\u30ca\u30e0\u306e16,000\u4eba\u306b\u3082\u53ca\u3076\u7b2c\uff13\u76f8\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3088\u308b\u91cd\u75c7\u5316\u4e88\u9632\u52b9\u679c\u306f<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">95.3\uff05<\/mark><\/strong>\u3001\u767a\u75c7\u4e88\u9632\u52b9\u679c\u306f<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">56.6\uff05<\/mark><\/strong>\u3067\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u30c7\u30eb\u30bf\u682a\u6d41\u884c\u671f\u304c\u4e3b\uff09<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u5f93\u6765\u306emRNA\u30ef\u30af\u30c1\u30f3\u3088\u308a\u3082\u5c11\u91cf\u3067\u4e88\u9632\u52b9\u679c\u304c\u9577\u304f\u7d9a\u304f\u30dd\u30c6\u30f3\u30b7\u30e3\u30eb\u3092\u6301\u3064\u306e\u304c\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u6700\u5927\u306e\u5f37\u307f\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.thelancet.com\/journals\/laninf\/article\/PIIS1473-3099(24)00060-4\/fulltext\" title=\"\">Persistence of immune responses of a self-amplifying RNA COVID-19 vaccine (ARCT-154) versus BNT162b2<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11094049\/\" title=\"\">Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials<\/a>\uff09<\/p>\n\n\n<ins class=\"adsbygoogle\"\n        style=\"display:block; text-align:center;\"\n        data-ad-layout=\"in-article\"\n        data-ad-format=\"fluid\"\n        data-ad-client=\"ca-pub-5748007460615735\"\n        data-ad-slot=\"4711491386\"><\/ins>\n        <script>\n        (adsbygoogle = window.adsbygoogle || []).push({});\n        <\/script>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%81%AE%E5%AE%89%E5%85%A8%E6%80%A7%E3%82%84%E5%89%AF%E4%BD%9C%E7%94%A8%E3%81%AF%EF%BC%9F\"><\/span>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306e\u5b89\u5168\u6027\u3084\u526f\u4f5c\u7528\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-1-1.webp\" alt=\"\" class=\"wp-image-7867 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-1-1.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-1-1-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-1-1-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p>\u5b9f\u306f\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u958b\u767a\u3059\u308b\u306b\u3042\u305f\u3063\u3066\u306f\u3001\u304b\u306a\u308a\u614e\u91cd\u306b\u884c\u3063\u3066\u304d\u305f\u3053\u3068\u304c\u3046\u304b\u304c\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u30d9\u30c8\u30ca\u30e0\u3067\u306f2021\u5e74\u304b\u3089\u73fe\u5728\u9032\u884c\u4e2d\u3067\u4e8c\u91cd\u76f2\u691c\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u304c\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u5f8c\u671f\u30d5\u30a7\u30fc\u30ba\u3067\u3042\u308b\u7b2c\uff13\u76f8\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u30b3\u30b9\u30bf\u30a4\u30d9\u3068\u30d7\u30e9\u30bb\u30dc\uff08\u507d\u85ac\uff09\u3092\u305d\u308c\u305e\u308c\u7d048,000\u4eba\u305a\u3064\u6295\u4e0e\u3057\u3001\u5408\u8a0816,000\u4eba\u3068\u3044\u3046\u975e\u5e38\u306b\u5927\u898f\u6a21\u306a\u81e8\u5e8a\u8a66\u9a13\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u56fd\u5185\u3067\u3082\u7b2c\uff13\u76f8\u81e8\u5e8a\u8a66\u9a13\u3092\u65e5\u672c\u306e\u5916\u6765\u81e8\u5e8a\u65bd\u8a2d11\u65bd\u8a2d\u5171\u540c\u3067\u884c\u308f\u308c\u30012022\u5e7412\u6708\u304b\u3089\u5b89\u5168\u6027\u304c\u8ffd\u53ca\u3055\u308c\u3066\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u56fd\u5185\u5916\u3067\u8003\u3048\u308b\u3068\u30012\uff5e3\u5e74\u306e\u5e74\u6708\u3092\u7d4c\u3066\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u5b9f\u969b\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3067\u3069\u306e\u3088\u3046\u306a\u526f\u4f5c\u7528\u304c\u51fa\u305f\u306e\u304b\u3002\u30d9\u30c8\u30ca\u30e0\u306e16,000\u4f8b\u306b\u53ca\u3076\u81e8\u5e8a\u8a66\u9a13\u306b\u3088\u308b\u3068\u3001\u983b\u5ea6\u5225\u306b\u4ee5\u4e0b\u306e\u526f\u4f5c\u7528\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002\uff081\u56de\u63a5\u7a2e\uff09<\/p>\n\n\n\n<ul 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class=\"wp-block-list\">\n<li><strong>\u5c40\u6240\u306e\u7d05\u6591<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d912.4%\u3001\u30b3\u30df\u30ca\u30c6\u30a320.8% <\/li>\n\n\n\n<li><strong>\u5c40\u6240\u306e\u786c\u7d50<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d912.4%\u3001\u30b3\u30df\u30ca\u30c6\u30a319.9% <\/li>\n\n\n\n<li><strong>\u5c40\u6240\u306e\u5727\u75db<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d992.4%\u3001\u30b3\u30df\u30ca\u30c6\u30a395.8% <\/li>\n\n\n\n<li><strong>\u5c40\u6240\u306e\u75bc\u75db<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d983.8%\u3001\u30b3\u30df\u30ca\u30c6\u30a387.7% <\/li>\n\n\n\n<li><strong>\u767a\u71b1<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d920.0%\u3001\u30b3\u30df\u30ca\u30c6\u30a318.6% <\/li>\n\n\n\n<li><strong>\u95a2\u7bc0\u75db<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d926.7%\u3001\u30b3\u30df\u30ca\u30c6\u30a327.7%<\/li>\n\n\n\n<li> <strong>\u60aa\u5bd2<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d930.0%\u3001\u30b3\u30df\u30ca\u30c6\u30a325.2% <\/li>\n\n\n\n<li><strong>\u4e0b\u75e2<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d96.7%\u3001\u30b3\u30df\u30ca\u30c6\u30a34.2% <\/li>\n\n\n\n<li><strong>\u3081\u307e\u3044<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d96.0%\u3001\u30b3\u30df\u30ca\u30c6\u30a33.2% <\/li>\n\n\n\n<li><strong>\u982d\u75db<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d939.3%\u3001\u30b3\u30df\u30ca\u30c6\u30a330.6% <\/li>\n\n\n\n<li><strong>\u5026\u6020\u611f<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d944.8%\u3001\u30b3\u30df\u30ca\u30c6\u30a343.1% <\/li>\n\n\n\n<li><strong>\u60aa\u5fc3<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d95.0%\u3001\u30b3\u30df\u30ca\u30c6\u30a33.9% <\/li>\n\n\n\n<li><strong>\u7b4b\u8089\u75db<\/strong>\uff1a\u30b3\u30b9\u30bf\u30a4\u30d929.3%\u3001\u30b3\u30df\u30ca\u30c6\u30a324.5%<\/li>\n<\/ul>\n\n\n\n<p>\u3068\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u30ef\u30af\u30c1\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u3082\u3001\u307b\u307c\u5909\u308f\u3089\u306a\u3044\u526f\u4f5c\u7528\u767a\u73fe\u7387\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u6709\u5bb3\u4e8b\u8c61\u306e\u767a\u73fe\u307e\u3067\u306e\u65e5\u6570\u3068\u6301\u7d9a\u671f\u9593\u306f\u30b3\u30b9\u30bf\u30a4\u30d9\u3068\u30b3\u30df\u30ca\u30c6\u30a3\u3067\u5927\u304d\u306a\u5dee\u306f\u306a\u3044\u3068\u3057\u3066\u3044\u308b\u306e\u3067\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u304c\u5f93\u6765\u306emRNA\u30ef\u30af\u30c1\u30f3\u3068\u540c\u3058\u304f\u3089\u3044\u306e\u526f\u4f5c\u7528\u3068\u3044\u3048\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.thelancet.com\/journals\/laninf\/article\/PIIS1473-3099(24)00060-4\/fulltext\" title=\"\">Persistence of immune responses of a self-amplifying RNA COVID-19 vaccine (ARCT-154) versus BNT162b2<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11094049\/\" title=\"\">Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials<\/a>\uff09<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%83%AC%E3%83%97%E3%83%AA%E3%82%B3%E3%83%B3%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%82%92%E6%89%93%E3%81%A4%E3%81%A8%E5%85%A5%E5%BA%97%E3%81%8A%E6%96%AD%E3%82%8A%E3%80%81%E3%81%AF%E6%AD%A3%E3%81%97%E3%81%84%E3%81%AE%E3%81%8B%EF%BC%9F\"><\/span>\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3064\u3068\u5165\u5e97\u304a\u65ad\u308a\u3001\u306f\u6b63\u3057\u3044\u306e\u304b\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-2.webp\" alt=\"\" class=\"wp-image-7868 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-2.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-2-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-2-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/675;\" \/><\/figure>\n\n\n\n<p>\u3055\u3066\u3001SNS\u306a\u3069\u3092\u4e2d\u5fc3\u306b\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u304c\u975e\u5e38\u306b\u907f\u96e3\u306e\u7684\u306b\u306a\u3063\u3066\u304a\u308a\u3001\u4e2d\u306b\u306f\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3063\u305f\u65b9\u306f\u5165\u5e97\u304a\u65ad\u308a\u300d\u3068\u3044\u3046\u5e97\u307e\u3067\u73fe\u308c\u308b\u81ea\u4f53\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u770b\u8b77\u502b\u7406\u5b66\u4f1a\u304c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3078\u306e\u61f8\u5ff5\u3068\u3057\u3066\u300c\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306e\u554f\u984c\u300d\u3092\u5f15\u304d\u5408\u3044\u306b\u51fa\u3057\u305f\u3053\u3068\u304b\u3089\u62cd\u8eca\u304c\u304b\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3068\u306f\u4e00\u8a00\u3067\u3044\u3046\u3068\u300c\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u308a\u30ef\u30af\u30c1\u30f3\u306e\u6210\u5206\u304c\u4ed6\u306b\u4f1d\u64ad\u3057\u3066\u75c5\u6c17\u306b\u306a\u308b\u300d\u3068\u3044\u3046\u7406\u8ad6\u3002<\/p>\n\n\n\n<p>2021\u5e74\u3067\u306e\u4eee\u8aac\u6bb5\u968e\u306e\u8ad6\u6587(\u8ad6\u6587\u306e\u8cea\u306f\u30a4\u30f3\u30d1\u30af\u30c8\u30d5\u30a1\u30af\u30bf\u30fc\u304c\u3064\u304b\u306a\u3044\u304f\u3089\u3044\u4f4e\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff09\u304c\u767a\u7aef\u3067\u3059\u3002\u540c\u8ad6\u6587\u3067\u306f\u300c\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u3063\u3066\u4f53\u5185\u3067\u751f\u6210\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001\u8aa4\u3063\u3066\u6298\u308a\u7573\u307e\u308c\u3001\u30d7\u30ea\u30aa\u30f3\u3068\u547c\u3070\u308c\u308b\u7570\u5e38\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5909\u5316\u3059\u308b\u53ef\u80fd\u6027\u300d\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u300c\u30d7\u30ea\u30aa\u30f3\u304c\u4f53\u5185\u306e\u3042\u3089\u3086\u308b\u5834\u6240\u306b\u904b\u3070\u308c\u3001\u547c\u5438\u3084\u76ae\u819a\u63a5\u89e6\u306a\u3069\u306b\u3067\u4ed6\u306e\u4eba\u306b\u3046\u3064\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u300d\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u8ad6\u6587\u3067\u3082\u300c\u3053\u308c\u306f\u53ef\u80fd\u6027\u3067\u3042\u308a\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u300d\u3068\u7d50\u8ad6\u3065\u3051\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u7406\u8ad6\u304c\u5b9f\u8a3c\u3055\u308c\u305f\u3082\u306e\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u540c\u7406\u8ad6\u306fmRNA\u30ef\u30af\u30c1\u30f3\u304b\u3089\u306e\u7406\u8ad6\u3067\u3042\u308a\u3001\u4eee\u306b\u540c\u7406\u8ad6\u304c\u6b63\u3057\u3044\u3068\u3057\u3066\u3082\u3001\u307b\u3068\u3093\u3069\u306e\u4eba\u304cmRNA\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3063\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u304b\u3089\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-black-color\">\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u3060\u3051\u5165\u5e97\u304a\u65ad\u308a\u300d\u3068\u3044\u3046\u306e\u306f\u3042\u307e\u308a\u7406\u8ad6\u7684\u306a\u88cf\u4ed8\u3051\u306b\u4e4f\u3057\u3044<\/mark><\/strong>\u3068\u611f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u305d\u3053\u3060\u3051\u5165\u5e97\u62d2\u5426\u3057\u3066\u3082\u6e80\u54e1\u96fb\u8eca\u306b\u4e57\u3063\u3066\u307f\u306a\u3055\u3093\u4ed5\u4e8b\u306b\u884c\u304f\u308f\u3051\u3067\u3059\u3057\u30012\uff5e3\u5e74\u524d\u304b\u3089\u30d9\u30c8\u30ca\u30e0\u30678,000\u540d\u3001\u65e5\u672c\u3067400\u540d\u4ee5\u4e0a\u306f\u6cbb\u9a13\u3067\u63a5\u7a2e\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u3057\u304b\u3082\u4e8c\u91cd\u76f2\u691c\u3067\u3069\u3061\u3089\u3092\u6253\u3063\u3066\u3044\u308b\u304b\u308f\u304b\u3089\u306a\u3044\uff09\u306e\u3067\u3001\u3053\u308c\u304b\u3089\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u3092\u304a\u65ad\u308a\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u4e88\u9632\u52b9\u679c\u306f\u306a\u3044\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u4ed6\u306e\u8ad6\u6587\uff08\u4eca\u5ea6\u306f\u304d\u3061\u3093\u3068\u8ad6\u6587\u306e\u8cea\u304c\u62c5\u4fdd\u3055\u308c\u305f\u8ad6\u6587\u3067\u3059\uff09\u3067\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u3068\u672a\u63a5\u7a2e\u8005\u304c\u305d\u308c\u305e\u308c\u30b3\u30ed\u30ca\u611f\u67d3\u3057\u305f\u3068\u304d\u3001\u3069\u308c\u304f\u3089\u3044\u30a6\u30a4\u30eb\u30b9\u304c\u6392\u51fa\u3055\u308c\u305f\u304b\uff08\uff1d\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3055\u308c\u305f\u304b\uff09\u3092\u898b\u305f\u8ad6\u6587\u3067\u306f\u3080\u3057\u308d\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u308a\u3001\u767a\u75c7\u304b\u30895\u65e5\u4ee5\u964d\u306b\u30a6\u30a4\u30eb\u30b9\u3092\u6392\u51fa\u3059\u308b\u78ba\u7387\u304c\u4f4e\u4e0b\u3057\u305f\uff08\uff1d\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3055\u308c\u306a\u304b\u3063\u305f\uff09\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u304a\u305d\u3089\u304f\u514d\u75ab\u304c\u304d\u3061\u3093\u3068\u8a98\u5c0e\u3055\u308c\u3001\u4f53\u5185\u306e\u30a6\u30a4\u30eb\u30b9\u91cf\u81ea\u4f53\u304c\u6e1b\u3063\u305f\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u306d\u3002\u3080\u3057\u308d\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u3063\u3066\u30b3\u30ed\u30ca\u81ea\u4f53\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306f\u8d77\u3053\u308a\u306b\u304f\u304f\u306a\u308b\u308f\u3051\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u307f\u3093\u306a\u8272\u3005\u306a\u60f3\u3044\u304c\u3042\u308a\u3001\u30ef\u30af\u30c1\u30f3\u306e\u7a2e\u985e\u3092\u9078\u3093\u3067\u63a5\u7a2e\u3057\u307e\u3059\u3002\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3055\u308c\u305f\u65b9\u3078\u306e\u300c\u304a\u65ad\u308a\u300d\u304c\u5e83\u304c\u3089\u306a\u3044\u3053\u3068\u3092\u5207\u306b\u9858\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3082\u3061\u308d\u3093\u5f53\u9662\u3067\u306f\u308f\u3056\u308f\u3056\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3063\u3066\u3044\u307e\u3059\u304b\uff1f\u300d\u3068\u805e\u3044\u3066\u3001\u6253\u3063\u3066\u3044\u305f\u5834\u5408\u8a3a\u7642\u3092\u62d2\u5426\u3059\u308b\u306a\u3069\u3068\u3044\u3046\u3053\u3068\u306f\u3057\u307e\u305b\u3093\u3002\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306b\u3064\u3044\u3066\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u30ec\u30d9\u30eb\u304c\u9ad8\u3044\u30c7\u30fc\u30bf\u304c\u3042\u308b\u3068\u5224\u65ad\u3057\u305f\u5834\u5408\u306f\u8ffd\u8a18\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.jnea.net\/news\/cat-statement\/post-655\/\" title=\"\">\u65e5\u672c\u770b\u8b77\u502b\u7406\u5b66\u4f1a\u300c\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u7dca\u6025\u58f0\u660e\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u300d<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.researchgate.net\/publication\/359198537_Worse_Than_the_Disease_Reviewing_Some_Possible_Unintended_Consequences_of_the_mRNA_Vaccines_Against_COVID-19\" title=\"\">Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9499220\/\" title=\"\">Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study<\/a>\uff09<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%BD%93%E9%99%A2%E3%81%A7%E3%81%AF%E3%80%8C%E3%83%95%E3%82%A1%E3%82%A4%E3%82%B6%E3%83%BC%E7%A4%BE%E8%A3%BD%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3%E3%80%8D%E3%82%92%E6%8E%A1%E7%94%A8%E3%81%97%E3%81%A6%E3%81%84%E3%81%BE%E3%81%99\"><\/span>\u5f53\u9662\u3067\u306f\u300c\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u88fd\u30ef\u30af\u30c1\u30f3\u300d\u3092\u63a1\u7528\u3057\u3066\u3044\u307e\u3059<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"900\" height=\"675\" data-src=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-3.webp\" alt=\"\" class=\"wp-image-7869 lazyload\" data-srcset=\"https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-3.webp 900w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-3-300x225.webp 300w, https:\/\/soujinkai.or.jp\/himawariNaiHifu\/wp-content\/uploads\/2024\/10\/\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3-3-768x576.webp 768w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; 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